Farkhanadah Sarfraz
University of Sargodha, Pakistan
Title: Studies on hypolipidemic potentials of synbiotic yoghurt
Biography
Biography: Farkhanadah Sarfraz
Abstract
Hyperlipidemia is a metabolic disorder categorized by elevated blood cholesterol levels. Hypercholesterolemia is a risk factor for many chronic diseases like hypertension, cardiac failure, and atherosclerosis. Synbiotic is a synergistic combination of probiotics (beneficial microbes) and prebiotics (indigestible carbohydrates) that may possess cholesterol lowering ability. Antihyperlipidemic effect of synbiotic yoghurt (developed by fructo-oligosacchride and isomalto-oligosacchride) was examined in hyperlipidemic rabbits as an animal model. Hyperlipidemic condition in rabbits was induced through hyperlipidemic diet. After induction, hyperlipidemic rabbits were fed on treatment diet containing synbiotic yoghurt in various concentrations (0%, 2%, 4%, and 6%). During study period of 4 weeks the blood lipid count of animals i.e., total cholesterol, triglycerides, high density lipoproteins, low density and very low density lipoproteins was analyzed after every week. The overall results indicated a significant decline in total cholesterol (80%) triglycerides, low density lipoprotein and very low density lipoprotein contents. Only high density lipoprotein contents were increased 53.70±0.35 mg/dl (415.21%). So it was concluded from the results of study that synbiotic yoghurt (6g/Kg) possesses hypolipidemic potential.